A function that perform normalisation for alternative expression
normaliseExprs( sce, altExp_name = NULL, exprs_value = "counts", transform = c("log", "clr", "zi_minMax", "minMax"), log_offset = NULL )
sce | A |
---|---|
altExp_name | Name of alternative expression that will be used to perform normalisation |
exprs_value | A character indicates which expression value in assayNames is used. |
transform | type of transformation, either log or clr (Centered log ratio transform) |
log_offset | Numeric scalar specifying the pseudo-count to add when log-transforming expression values. Default is 1 |
a SingleCellExperiment object
data(CITEseq_example, package = "CiteFuse") sce_citeseq <- preprocessing(CITEseq_example) sce_citeseq <- normaliseExprs(sce = sce_citeseq, altExp_name = "ADT", transform = "log")