Traverse a gating tree for a single cell and compute node-wise marker scores
along the deterministic path defined by comparing marker expression to each
node's cutoff.
Usage
collect_path_scores(tree, expr_mat, cell_i)
Arguments
- tree
A gating tree as produced by [build_fullcoverage_tree()].
- expr_mat
Numeric matrix-like expression object with markers in rows and
cells in columns (e.g. `assay(spe, "norm")`). Row names must include marker names.
- cell_i
Integer index of the cell/column to score.
Value
A numeric vector of per-node scores (may contain `NA_real_` if a marker value
is not finite for that cell).
Examples
tree <- list(
type = "node", marker = "CD3", cutoff = 1, scale = 0.5,
left = list(type = "leaf"), right = list(type = "leaf")
)
expr_mat <- rbind(CD3 = c(0.5, 1.5))
collect_path_scores(tree, expr_mat, cell_i = 1)
#> [1] 0.2689414
